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[RC] Long term use of Adequan and/or joint injections ...? - steelsidedown

I apologize, as this is spurred on by another list. 
 
The current conversation pretains to damage caused by use of Adequan, both IM and diectly in joint.  As in, joints actually getting worse over time from the use of this product/method.
 
I have only heard positive things about the use of this product/method... 
 
Can anyone elaborate? (for or against)
 
I haven't been able to find any research online.
 
Jen