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[RC] Gamma-oryzanol & testosterone - k s swigart


Stefanie Prasch said:


But the reason gamma-oryzanol is banned is that its
?supposed to build up testosterone.


From this study:

http://content.nhiondemand.com/psv/view-abs.asp?fnid=112872&absid=105717

"Intravenous or subcutaneous injections of gamma-oryzanol in rats have been 
shown to suppress luteinizing hormone release, reduce growth hormone synthesis 
and release, and increase release of the catecholamines, dopamine and 
norepinephrine, in the brain. Although it hasn't been directly measured, this 
metabolic milieu, if accurate, may actually reduce testosterone production."

While gamma-oryzanol may have claims that it builds up testosterone (and other 
anabolics), there have been no studies done to show that to be true and at 
least one to show that it has the opposite effect.? 

So...


We had a case of a successful rider who gave his horse
?some muscle building supplement food, declared
?doping-free by the feeding-company. This stuff had
?extra gamma-oryzanol in it and caused a slightly too
?high testosterone-level with his gelding.


I would be more inclined to believe that the "slightly too high 
testosterone-level" in this gelding was not caused by having fed too much 
gamma-oryzanol to the horse but rather would suspect that a) the muscle 
building supplement was not as "doping-free" as the feed company claimed, b) 
that this was not the only muscle building supplement that the rider had been 
giving the horse, or c) that the gelding fell outside of the range of normal 
for geldings and produced "slightly too high" of testosterone level within his 
own body.

ALL horses produce testosterone (even mares, in fact, mares generally produce 
more testosterone than geldings do).? The adrenal glands produce testosterone.? 
It is not impossible that a gelding might produce significantly more 
testosterone than the average gelding simply because not all horses are average.

It might have been the gamma-oryzanol, but it might have been something else as 
well.

What limited studies that have been done on assorted species are pretty much 
inconclusive as to whether it has any muscle building effects.? There are no 
studies showing that it effects testosterone production and a few that show it 
has the opposite effect on testosterone.

All of this, however, doesn't change the truth of this:


So the usual rice-bran diet probably shouldn't lead to
positive drug testing atm. So far the practical side, but
?still makes you do something "illegal" when you feed
?food containing gamma-oryzanol.


The way the current AERC rule reads, it is against the rule to feed any 
gamma-oryzanol to your horse, whether there is a test that can catch you at it 
or not.

Some people don't care if something is against the rules as long as they can't 
get caught breaking them, but some people do.? And personally, those that do 
are the ones that _I_ would rather play with.

kat
Orange County, Calif.
:)

p.s.? If the only reason for banning gamma-oryzanol is that it boosts 
testosterone; there would be no reason to ban it.? It is already against the 
rules to boost testosterone (and there is a test for it) no matter what 
mechanism you use for doing it...except leaving your stallion intact.? That is 
legal.

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