Our Lyric has multiple food and environmental allergies. She has had hives on multiple occasions. We found that we had to eliminate the offending food and things got much better. Then the studies on the omega 3 and 6's came out. We then balanced these and oh what a difference! By this I mean you need to have a specific ratio of 3's to 6's. I believe it is 5 omega 3's to every 1 omega 6. The Platinum folks have lots of info on their web site and have supplements for allergies(http://www.platinumperformance.com/animal/equine/research/#) They have done the research in a scientific manner. They also have PhD prepared horse nutritionists who will help you help your horse. Good luck!