[RC] Update "mystery lameness" injury and question about new drug - Jennifer ThompsonDear list,The following is the latest on Shahtahr, my 10 yr old Arab gelding. Any input or thoughts on his present condition are welcomed, as at this point, I don't know whether he will ever do a ride again :( Am also wondering if anybody has heard of or used Tildren (tiludronate - a biophosphonate), a new drug being used in France (manufacturer is CEVA) for the treatment of navicular sydrome - it supposedly stops the reabsorbtion of bone and formation of invaginations, allowing the lesions and channels to fill back in and even out rough surfaces of the nav bone. This drug is used in humans for Paget's disease and osteoporosis. I can't find much info on long-term effects or safety. It is very expensive ($1500 for a one-time 10-day treatment) and not easily obtained here in the U.S. Studies show amazing short-term results so far -- 60% or greater sucess rate of restoring bone density to navicular bones. Even better sucess rates if treated within 6 months of initial onset of signs. Anyway, the update: It's been 3.5 months since he was grade 3 lame on his right front, and diagnosed via x-rays, CAT scan, and bone scan as having torn a small ligament away from medial side of his navicular bone. The ligament is called the "suspensory ligament of the navicular bone" or the "sesamoidian collateral ligament". It is a rare injury and because of lack of case studies, his prognosis was unclear. The bone scan showed a lot of activity on the top medial surface of the navicular bone, indicating ongoing inflammation and boney changes at the ligament's attachment site. He was put into bar shoes (set under) with 2 degree wedge pads and we got very aggressive with shortening and rockering his toes. He was also put on a silicon bone supplement called Osteon, by the Platinum Performance folks. He has been on stall rest with 15 mins a day handwalking up until now (3.5 months). We just returned from our re-check at the clinic, where he got a followup bone scan and new x-rays. Results are as follows: On initial exam, he was pronounced clinically sound at the trot, both on the straight and lunged in a circle both ways. X-rays show the formation of two very tiny enthesiophytes (spurs) at the ligament's attachment site, which was pretty much expected to happen and they are so small that right now, the vet is not too concerned since he is trotting sound. On the down side, X-rays also showed that his navicular bone is now showing an increase of invaginations (the channels that form on the distal ridge in a horse with navicular disease). This is a new development, and the vet feels that the navicular bone may be remodeling as a secondary response to one branch of the ligament being torn away from it, causing uneven torque or pressure on the bone. This is cause for some concern...we don't know if this will resolve itself with time as the ligament injury heals completely and the foot resumes a more normal state or if it will continue to worsen - basically a case of injury-induced navicular disease. The bone scan showed that the site of the initual injury (ligament attachment site on the top/medial surface of the NB) is now totally "cold" - no inflammation at all - which is great news. It glowed like a Christmas tree on his first bone scan. But the rest of the navicular bone is now active, but vet said it is mild at this point. He showed me scans of horses with NB's that were really glowing on the screen...Shahtahr's is pretty minimal compared to those, but it could worsen. It's an unknown at this time. I begin re-introduction to exercise tomorrow, starting with 30 mins/day under saddle at a walk. After that, add in 5 minutes trot for 3 weeks, so on and so forth (I've a page-long regimen to follow). He can keep progressing unless we backslide and he shows soreness again. The vet advised keeping him in bar shoes and pads, but weaning him off the wedges, going down to 1 degree for a while and then nothing - but keeping the eggbars and pads forever, which I'm not thrilled about. I've read somewhere that bar shoes really don't help protect/stabilize the foot as well as was once thought, but I guess the vet knows best. I just hate to think of a lifetime in those things and pads...his feet get so gunky under there. I hope he can some day go back into his Natural Balance shoes and even go barefoot during winter. That's all I know at this point. Who would have thought I'd end up with an Arabian with navicular problems, albeit acquired in a roundabout way. Don't know if he'll ever be a distance horse again - depends on what his navicular bone does. I'll have to take it a step at a time. Will let everyone know how we're coming along farther down the road. Thanks for reading and any thoughts. Right now I am trying to decide whether to ride this out and see what happens in regards to the new navicular bone changes, or go ahead with the Tildren treatment. Jennifer =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-= Ridecamp is a service of Endurance Net, http://www.endurance.net. Information, Policy, Disclaimer: http://www.endurance.net/Ridecamp Subscribe/Unsubscribe http://www.endurance.net/ridecamp/logon.asp Ride Long and Ride Safe!! =-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=-=
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