ridecamp@endurance.net: Two interesting papers

Two interesting papers

Tivers (Tivers@aol.com)
Wed, 10 Dec 1997 00:53:02 EST

These new papers pertain to some discussions we've had in the past. The first
demonstrates the efficacy of oral GAGs while the second says that magnetic
energy relieves pain.

ti

Authors RR Hanson, LR Smalley, GK Huff, S White, TA Hammad
Title Oral Treatment with a Glucosamine-Chondroitin Sulfate Compound for
Degenerative Joint Disease in Horses - 25 Cases
Full source Equine Practice, 1997, Vol 19, Iss 9, pp 16
KeyWords Plus POLYSULFATED GLYCOSAMINOGLYCAN; OSTEOARTHRITIS; BIOCHEMISTRY;
CARTILAGE; MATRIX
TGA/Book No. YD960
Discipline Veterinary Science & Medicine
Document type Article
Language English
Address Hanson RR, Auburn Univ, Coll Vet Med, Dept Large Anim Surg & Med,
Auburn,AL 36849 USA
ISBN/ISSN 0162-8941
Publisher Veterinary Practice Publ Co, 3 Burroughsdr, Irvine, CA 92618-2804
Abstract Twenty-five horses with degenerative joint disease that fit the
conditions of the study were treated with a glucosamine-chondroitin sulfate
compound (Cosequin(R):Nutramax Laboratories, Inc., Baltimore, MD) to evaluate
its effectiveness in decreasing lameness. All horses were confirmed to have
degenerative joint disease (DJD) by physical examination, diagnostic
intraarticular anesthesia, and radiographs or fluoroscopy of the distal
interphalangeal, metacarpophalangeal, tarsometatarsal or carpal joints. All
horses weighing less than 545 kg were given 9 g of the glucosamine-chondroitin
sulfate compound orally twice daily for 6 weeks. Horses weighing more than 545
kg were given 12 g twice daily for 6 weeks. Each 3-g measure included 1,800 mg
of glucosamine hydrochloride, 600 mg of purified chondroitin sulfate, 16 mg of
manganese, and 104 mg of ascorbate. Lameness grade, flexion test grade and
stride length (cm) were measured at an initial examination and re-evaluated at
4 and 6 week follow-up examinations. Repeated measurement analysis was
implemented to assess the lameness using SAS computer package (Statistical
Analysis System, Cary, NC). Within 2 weeks of the start of administration of
the glucosamine-chondronin sulfate compound, the lameness grade, flexion test,
and stride length were significantly (P < 0.001) improved. A further
significant improvement in lameness was evident at 4 weeks, (p = 0.04), while
flexion score (p = 0.2) and stride length (P = 0) did not show further
improvement. The age of horses was not a significant factor in the improvement
of the lameness grade, flexion test, or stride length (p = 0.2, p = 0.7 and p
= 0.2, respectively), implying that the achieved results were true
irrespective of horse age.

Authors C Vallbona, CF Hazlewood, G Jurida
Title Response of Pain to Static Magnetic-Fields in Postpolio Patients - A
Double-Blind Pilot-Study
Full source Archives of Physical Medicine and Rehabilitation, 1997, Vol 78,
Iss 11, pp 1200-1203
KeyWords Plus ELECTROMAGNETIC-FIELDS; BIOLOGICAL-SYSTEMS; MECHANISM
TGA/Book No. YE945
Discipline Sports Science & Medicine
Document type Article
Language English
Address Vallbona C, Baylor Coll Med, Dept Family & Community Med, 1 Baylor
Plaza, Houston,TX 77030 USA
ISBN/ISSN 0003-9993
Publisher W B Saunders Co, Independence Square West, Curtis Center, Ste 300,
Philadelphia, PA 19106-3399
Abstract Objective: To determine if the chronic pain frequently presented by
postpolio patients can be relieved by application of magnetic fields applied
directly over an identified pain trigger point. Design: Double-blind
randomized clinical trial. Setting: The postpolio clinic of a large
rehabilitation hospital. Patients: Fifty patients with diagnosed postpolio
syndrome who reported muscular or arthritic-like pain. Intervention:
Application of active or placebo 300 to 500 Gauss magnetic devices to the
affected area for 45 minutes. Main Outcome Measure: Score on the McGill Pain
Questionnaire. Results: Patients who received the active device experienced an
average pain score decrease of 4.4 +/- 3.1 (p < .0001) on a 10-point scale.
Those with the placebo devices experienced a decrease of 1.1 +/- 1.6 points (p
< .005). The proportion of patients in the active-device group who reported a
pain score decrease greater than the average placebo effect was 76%, compared
with 19% in the placebo-device group (p < .0001). Conclusions: The application
of a device delivering static magnetic fields of 300 to 500 Gauss over a pain
trigger point results in significant and prompt relief of pain in postpolio
subjects.

Home Events Groups Rider Directory Market RideCamp Stuff