Re: [RC] carrier status and Strep. equi - CMNewell
Although the poster was mistaken about viruses vs. bacteria, he was on
target with remarks about carriers.
Equine Vet J 2000 Nov;32(6):527-32
Elimination of guttural pouch infection and inflammation in asymptomatic
carriers of Streptococcus equi.
Verheyen K, Newton JR, Talbot NC, de Brauwere MN, Chanter N.
Centre for Preventive Medicine, Animal Health Trust, Newmarket, Suffolk, UK.
Three protracted outbreaks of strangles were investigated using endoscopic
examination and a total of 14 asymptomatic carriers of Streptococcus equi
were identified of which 13 showed evidence of carriage in the guttural
pouch. Treatment was initiated to eliminate S. equi colonisation since
these animals posed an infectious risk to susceptible horses. Two further
horses were referred to us with severe guttural pouch pathology and from
which S. equi was cultured, and treatment of these cases is also
described. Treatment in the first instance was directed towards removal of
gross guttural pouch pathology as seen on endoscopic examination. This was
done with a combination of irrigation of the pouch with moderate to large
amounts of saline, suction of fluid material and endoscopic manipulation
of chondroids. Subsequently, antibiotic treatment was used to eliminate S.
equi infection. All animals received systemic antibiotics, in some cases
combined with topical antimicrobial treatment. Treatment was generally
regarded as successful when the guttural pouches appeared normal and S.
equi was not detected in nasopharangeal swabs and pouch lavages on 3
consecutive occasions. Successful treatment of one carrier required
surgical intervention due to occlusion of both guttural pouch pharyngeal
openings. Fourteen of 15 carriers were successfully treated by endoscopic
removal of inflammatory material and antibiotic treatment, without
surgical intervention. Five carriers originally given potentiated
sulphonamide (33%) required further therapy with penicillin or ceftiofur,
administered both systemically and topically, before S. equi infection and
associated inflammation of the guttural pouches were eliminated.
--CMNewell, DVM
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