We live in Ga. where almost all pasture is fescue. When we discovered our mare was "with child"Surprise. We didn't have a lot of options, so we put her on a small dry lot. And fed her bermuda hay, which also grows here, just more expensive. I bought her a round bale of it at a time. My vet said just take them off the last 3 months.(Kept the round bale in the barn).Took 3 round bales at 32. $ each for 90 days. Not really too much trouble here. Side note one the reasons so much fescue here is it grows from September to June. Even in winter if they are mild. Bermuda really only grows here from June to August. ----- Original Message ----- From: Lisa Redmond Sent: Tuesday, July 09, 2002 8:14 AM To: ridecamp Subject: Re: [RC] Pasture Let me ask a question here--when you took your mare off pasture, what did type of hay did you put her on? The reason I ask is that fescue hay is also toxic. The problem isn't limited to the fresh fescue. The toxins are very stable over time, so if they were getting any fescue hay at all, it defeated the purpose of removing them from the pasture.
The toxins themselves are cleared from the mare's system very rapidly--we know this because there is a significant increase in serum prolactin within twenty-four hours after you remove the endophyte from the diet. However, the effects on the steroid hormones take longer to reverse. If she was removed 100 days out, there should have been milk production without much problem, unless she was just predisposed to being a poor milker--unless she was still getting some of the toxins in her diet in some fashion. We know that it takes very little of the toxin to cause a problem---as Claudia pointed out, her pasture was only 50% fescue. We started seeing problems in the experiment station pastures that were becoming reinfested due to moving stock from infested pastures (seed is the only way the endophyte is transmitted). Made life difficult for me on the last study, some were so badly reinfested--one was up to 40%.
Having said all that--there's no question that there are residual effects, and in some cases I wouldn't expect complete perfection even at 100 days out, simply because it takes a while for the steroid hormones to readjust, and with plain withdrawal it takes longer than if they are being treated with Equidone.
Withdrawal isn't a cure-all...however, it does achieve the main goal which is to save lives. I saw the train wrecks that occurred when animals weren't withdrawn at all--the high mare and foal mortality, the suffering, the broken calving jacks, etc. Trust me--the problems associated with withdrawal seem minor in comparison. One very significant problem we see in mares that aren't treated or withdrawn is that the foals do not rotate into the proper position for delivery--they are usually 90 degrees out of plane, i.e., their spines are aligned with the mares' side instead of with their spines. The mare's pelvis just isn't designed for that, and the number of foals that get stuck is appalling. I saw some horrific results, trust me.
The fact that withdrawal alone isn't perfect, and the fact that not everyone who breeds horses in the fescue belt has the facilities or labor or money to keep mares off fescue for the majority of the pregnancy is why we searched so hard for the drug. Now, if the FDA would get off it's collective butt and finish approving it...sigh....
Lisa
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