I'm new to this and have heard about thumps, but can anyone explain, 
  physiologically, what thumps is and the mechanism that causes it?  Also, 
  are certain types of horses prone to it?  Thanks,
   
   
  In a nutshell, when the body becomes depleted of 
  electrolytes, the electrical transmission of neural signals between the brain 
  and muscles gets out of whack.  At the same time, the muscles themselves 
  become hyperirritable---it takes alot less neural stimulation for them to want 
  to contract.  So you have muscles that are getting tighter and crampier, 
  plus you don't have very well integrated signals frrm the brain telling the 
  muscles what to do.
   
  OK, a bit of anatomy.  Just underneath the 
  heart is the phrenic nerve which, among other things, ennervates the 
  diaphragm muscle---the big muscle that divides the chest cavity from the 
  abdomen and drives respiration.
   
  When the electrolytes get out of 
  balance/depleted, the electrical impulses traveling along the neurons aren't 
  very good, right?.  But because the phrenic nerve travels so close to the 
  heart, it starts to have a tendency to pick up the electrical signals 
  generated by the heart itself.  That electrical signal travels back to 
  the diaphragm which is just looking for any little signal to contract, and it 
  doesn't much care whether those signals are originating from the brain or the 
  heart.  The diaphragm contracts in time with the electrical input with 
  the heart---which is why you can basically check a thumping horse's heart rate 
  from fifty feet away.
   
  So a diaphragm contracting in time with the heart 
  is an indication that the horse has some fairly significant electrolytes 
  imbalances---if he didn't, you wouldn't have the disruptions in neural 
  transmission, and you wouldn't have the hyperirritable muscle 
  tissue.
   
  The thumping itself isn't a lethal 
  condition---probably uncomfortable and weird for the horse, but not 
  fatal.  BUT, it is an indicator that all is not well with the horse, 
  because poor neural/muscle integration to the diaphragm also mean the same 
  thing going on in other parts of the body---you're just not seeing outward 
  signs of it.  So that means poor neural stimulation to the hindgut, poor 
  muscle coordination and so on.
   
  So let's not blow thumps off, right?  It 
  needs to be paid attention to and needs to be fixed.
   
  Susan G